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. 2022 Aug 26;24(4):639. doi: 10.3892/etm.2022.11576

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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P79350 and LM22B-10 reverses the protective effect of PGG on viability and apoptosis of HG-induced MPC5 cells. (A) The MPC5 cell viability treated by PGG was determined by CCK-8 assay. The (B) viability and (C and D) apoptosis of HG-induced MPC5 cells with or without PGG treatment were determined by CCK-8 and TUNEL assays. Magnification, x200. (E) The expression of apoptosis-related proteins in HG-induced MPC5 cells with or without PGG treatment was detected by western blotting. ^*P<0.05 and ^***P<0.001. PGG, 1, 2, 3, 4, 6-penta-O-galloyl-β-D-glucose; HG, high glucose; MPC5, conditionally immortalized mouse podocytes.