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. 2022 Aug 31;24(4):642. doi: 10.3892/etm.2022.11579

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Copyright: © Luo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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TIGIT and PD-1 expression in CXCR5^- CD4⁺ T cells in patients with RA and the HC. (A) Representative dot plots of population gating. (B) Percentage of TIGIT⁺CXCR5^-CD4⁺T cells and the MFI of TIGIT in CXCR5^- CD4⁺ T cells between patients with RA and the HC. (C) Percentage of PD-1⁺ CXCR5^- CD4⁺ T cells and the MFI of PD-1 in CXCR5^- CD4⁺ T cells between patients with RA and the HC. HC, healthy controls; MFI, mean fluorescence intensity; PD-1, programmed cell death protein 1; RA, rheumatoid arthritis; TIGIT, T cell immunoreceptor with immunoglobulin and ITIM domain; SS, side scatter; PE, phycoerythrin; ECD, PE-Texas red.