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. 2022 Aug 31;24(4):642. doi: 10.3892/etm.2022.11579

Figure 5.

Figure 5

TIGIT+ PD-1+ CXCR5- CD4+ T cell levels are correlated with rheumatoid arthritis activity. The MFI of PD-1 in TIGIT+ PD-1+ CXCR5- CD4+ T cells was positively correlated with (A) DAS28-ESR and (B) VAS. (C) The MFI of PD-1 in TIGIT+ PD-1+ CXCR5- CD4+ T cells was decreased following treatment. DAS28, disease activity score 28; ESR, erythrocyte sedimentation rate; MFI, mean fluorescence intensity; PD-1, programmed cell death protein 1; TIGIT, T cell immunoreceptor with immunoglobulin and ITIM domain; CXCR5, C-X-C chemokine receptor type 5; VAS, visual analogue scale.