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. 2022 Aug 10;8(9):1731–1757. doi: 10.1021/acsinfecdis.2c00193

Table 1. Synergistic Activity of Polymyxin Analogues.

name ref FICIa pathogen antibiotic
PMBN (105) 0.013a E. coli rifampicin
PMBO (105) 0.013a E. coli rifampicin
PMBH (105) 0.020a E. coli rifampicin
DAPB (105) 0.043a E. coli rifampicin
SPR741 (106) 0.06 E. coli rifampicin
NAB739 (100) 0.126 A. baumannii rifampicin
NAB7061 (100) 0.055 E. coli rifampicin
a

FICI calculated using eq 1 from MIC values reported in the cited reference.