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. 2022 Aug 10;8(9):1731–1757. doi: 10.1021/acsinfecdis.2c00193

Table 2. Synergistic Activities of Dilipidated Polymyxin Analogues.

name ref FICI pathogen antibiotic hemolytic activitya
dilipid polymyxin 1 (107) 0.02 P. aeruginosa rifampicin <10% (1 h)
dilipid polymyxin 2 (107) 0.26 P. aeruginosa novobiocin <10% (1 h)
dilipid polymyxin 5 (107) 0.31 P. aeruginosa rifampicin <10% (1 h)
a

Non-hemolytic is defined as <10% hemolysis compared to positive control, with incubation times denoted in parentheses.