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. 2022 Aug 22;65(17):11776–11787. doi: 10.1021/acs.jmedchem.2c00791

Table 1. SAR (Biochemical and Cellular) and ADME Properties in Quinoline and Naphthyridine Seriesa.

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a

Details on the biochemical and cellular assay as well as on clearance (Clint) and permeability (MDCK-MDR1) can be found in the Experimental Section.