Table 6.
Helicobacter pylori infection and risk markers of cardiovascular diseases
| Variable | Number (%) | HP +ve n (%) | HP −ve n (%) | [t value; p-value] (X2 value; p-value) |
|---|---|---|---|---|
| Total cholesterol (g/l), Mean ± SD, (Range) | 215.38 ± 59.58, (86–412) | 223.2 ± 3.781 | 200.2 ± 5.096 | [3.562; 0.0004*] |
| Hypo cholesterol (< 150) | 59 (16.25) | 30 (50.85) | 29 (49.15) | (14.58; 0.0007*) |
| Normal (150 to 200) | 80 (22.03) | 45 (56.25) | 35 (43.75) | |
| Hyper cholesterol (> 200) | 224 (61.70) | 164 (73.21) | 60 (26.79) | |
| LDL (g/l), Mean ± SD, (Range) | 110.02 ± 45.21,(12.98 229.6) | 116.6 ± 2.954 | 97.26 ± 3.734 | [3.459; 0.0006*] |
| Hypo (< 90) | 130 (35.52) | 76 (58.46) | 54 (41.54) | (12.056; 0.0024*) |
| Normal (90 to 130) | 98 (26.99) | 59 (60.20) | 39 (39.80) | |
| Hyper (> 130) | 135 (37.19) | 104 (77.04) | 31(22.96) | |
| HDL (g/l), Mean ± SD, (Range) | 51.79 ± 21.03, (4.3–119) | 51.01 ± 1.366 | 52.92 ± 1.912 | [0.8027; 0.4227] |
| Hypo (< 40) | 142 (39.12) | 99 (69.72) | 43 (30.28) | (4.966; 0.0831) |
| Normal (40 to 60) | 185 (50.96) | 122 (65.94) | 63 (34.06) | |
| Hyper (> 60) | 36 (9.97) | 18 (50.00) | 18 () | |
| TGA (g/l), Mean ± SD, (Range) | 145.91 ± 61.94, (13.39–318) | 146.2 ± 3.513 | 142.5 ± 4.964 | [0.6168; 0.5378] |
| Hypo (< 40) | 6 (1.65) | 3 (50.00) | 3 (50.00) | (1.5816; 0.4535) |
| Normal (40–150) | 197 (54.26) | 126 (63.96) | 71 (36.04) | |
| Hyper (> 150) | 160 (44.07) | 110 (68.75) | 50 (31.25) | |
| BMI (kg/m2), Mean ± SD, (Range) | 24.79 ± 4.03, (16.30–37.6) | 24.84 ± 0.2515 | 24.7 ± 0.3862 | [0.3146; 0.7609]) |
| Normal (18.5–24.9) | 218 (60.05) | 142 (65.14) | 76 (34.86) | (0.1493; 0.9281) |
| Overweight (25–29.9) | 113 (31.12) | 76 (67.26) | 37 (32.74) | |
| Obesity (≥ 30) | 32 (8.81) | 21 (65.62) | 11 (34.38) | |
| DBP (mmHg), Mean ± SD, (Range) | 77.024 ± 11.21 (41–104) | 77.18 ± 0.7757 | 77.35 ± 0.925 | [0.1324; 0.8947] |
| Hypo (< 80) | 225 (61.98) | 146 (68.89) | 79 (31.11) | (1.10; 0.576) |
| Normal (80 to 90) | 78 (21.48) | 50 (64.10) | 28 (35.09) | |
| Hyper (> 90) | 60 (16.52) | 43 (71.67) | 17 (28.33) | |
| SBP (mmHg), Mean ± SD, (Range) | 124.11 ± 19.29 (80–191) | 121.7 ± 1.284 | 137 ± 12.3 | [1.732; 0.0841] |
| Hypo (< 120) | 163 (44.90) | 114 (69.94) | 49 (30.06) | (2.2252; 0.3287) |
| Normal (120 to 140) | 145 (39.94) | 91 (62.76) | 54 (37.24) | |
| Hyper (> 140) | 55 (15.15) | 34 (61.82) | 21 (38.18) | |
| Blood pressure (mmHg) | /, (41/80–104/191) | / | / | / |
| Hypo (< 120/80) | 152 (41.87) | 98 (64.47) | 54 (35.53) | (0.2373; 0.8881) |
| Normal (120–140/80–90) | 164 (45.17) | 110 (97.07) | 54 (2.93) | |
| Hyper (> 140/90) | 47 (12.94) | 31 (65.96) | 16 (34.04) | |
| Heart rate (beat/min) | 79.53 ± 12.10 (45–114) | 80.00 ± 0.8606 | 78.56 ± 1.12 | [0.9968; 0.3195] |
| Normal (60 to 100) | 287 (79.06) | 186 (64.81) | 101 (35.19) | (1.235; 0.5394) |
| Tachycardia (> 100) | 48 (13.22) | 35 (72.92) | 13 (27.08) | |
| Bradycardia (< 60) | 28 (7.71) | 18 (64.28) | 10 (35.72) |
HP: H. pylori; +ve: Positive; −ve: Negative; DBP: Diastolic blood pressure; SBP: Systolic blood pressure; SD: standard deviation; X2: Chi-square; Bold value with *: Significant