Table 7.
Relationship between Helicobacter pylori infection and dyslipidaemia, heart dysfunction, overweight/obesity adjusting with potential confounders (socio-economic lifestyle and medical history parameters) assessed by multivariable linear regression analysis
| Variable | Univariate logistic regression | Multivariate logistic regression | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p value | Model 1 | Model 2 | Model 3 | Model 4 | |||||
| OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |||
| Dyslipidemia | ||||||||||
| Hyper total cholesterol | 2.3324 (1.4935–3.6423) | 0.0002* | 2.5848 (1.6235–4.1155) | 0.0001* | 2.4100 (1.5324–3.7903) | 0.0001* | 2.3373 (1.4610–3.7391) | 0.0004* | 2.5944 (1.5766–4.2692) | 0.0002* |
| High LDL-C | 2.3096 (1.4289–3.7331) | 0.0006* | 2.5793 (1.5560–4.2754) | 0.0002* | 2.3600 (1.4550–3.8280) | 0.0005* | 2.3612 (1.4412–3.8684) | 0.0006* | 2.6794 (1.5839–4.5328) | 0.0002* |
| Low HDL-C | 1.3321 (0.8489–2.0902) | 0.2123 | 1.2658 (0.7919–2.0234) | 0.3247 | 1.3480 (0.8565–2.1216) | 0.1969 | 1.4080 (0.8786–2.2563) | 0.1550 | 1.4103 (0.8588–2.3160) | 0.1743 |
| High TG | 1.2620 (0.8129–1.9592) | 0.2327 | 1.1407 (0.7249–1.7951) | 0.5693 | 1.2714 (0.8154–1.9825) | 0.2894 | 1.2431 (0.7885–1.9598) | 0.3487 | 1.1116 (0.6918–1.7861) | 0.6620 |
| Heart dysfunction | ||||||||||
| High DBP | 1.3807 (0.7510–2.5384) | 0.2991 | 1.3082 (0.7348–2.3291) | 0.3614 | 1.4359 (0.7764–2.6554) | 0.2488 | 1.4466 (0.7600–2.7534) | 0.2609 | 1.6772 (0.8404–3.3474) | 0.1424 |
| High SBP | 0.8135 (0.4495–1.4723) | 0.4952 | 0.8575 (0.4655–1.5796) | 0.6218 | 0.8020 (0.4412–1.4578) | 0.4692 | 0.9498 (0.4999–1.8047) | 0.8751 | 0.9589 (0.4900–1.8764) | 0.9024 |
| Hypertension | 1.0060 (0.5270–1.9204) | 0.9855 | 1.0781 (0.5527–2.1032) | 0.8253 | 0.9874 (0.5151–1.8927) | 0.9695 | 1.0980 (0.5540–2.1760) | 0.7888 | 1.0866 (0.5292–2.2310) | 0.8210 |
| High heart rate | 1.4646 (0.7441–2.8829) | 0.2694 | 1.3885 (0.6947–2.7753) | 0.3529 | 1.4854 (0.7514–2.9366) | 0.2551 | 1.4730 (0.7065–3.0708) | 0.3015 | 1.3765 (0.6460–2.9330) | 0.4077 |
| BMI | ||||||||||
| Overweigh/Obesity | 1.0813 (0.6936–1.6859) | 0.7300 | 1.1474 (0.7240–1.8185) | 0.5585 | 1.1063 (0.7054–1.7349) | 0.6601 | 1.1104 (0.6992–1.7635) | 0.6571 | 1.1785 (0.7234–1.9201) | 0.5095 |
DBP: Diastolic blood pressure; SBP: Systolic blood pressure; N, n: Number, (95% CI): 95% confidence intervals; OR: Odd ratio. Bold value with *: Significant. Model 1: Adjusted with sociodemographic and economic factors (sex, gender and income level); Model 2: Adjusted with lifestyle factors (smoking, alcohol consumption, physical activity); Model 3: Adjusted with medical history (history of hypertension, diabetes mellitus, and obesity); Model 4: Adjusted for all the confounding factors (Sociodemographic and economic, lifestyle and medical history)