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. 2022 Aug 30;9:984291. doi: 10.3389/fmed.2022.984291

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Copyright © 2022 Korzeniewski, Sutton, Escudero and Roberts.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Conceptual model of the antecedents, correlates and potential sequelae in offspring of mothers with preeclampsia. (A) Pre-conception/environmental factors are associated hypertensive pregnancy disorders and developmental disorders; (B) Either by shared underlying mechanism or confounding, preeclampsia is often associated with fetal/placental diseases, congenital anomalies detected at birth, and downstream inflammation-related illnesses after birth; (C) Largely depending on the length of gestation (and therefore co-occurrence with fetal growth problems), preeclampsia is associated with heightened risks of multiple developmental disorders and also chronic cardiovascular disease.