Table 3.
Regression analysis of FA supplementation with HDCP and preeclampsia (nonusers group as reference).
| Nonuser | User | ||||||
|---|---|---|---|---|---|---|---|
| Non-FA (n = 1028) | Early pregnancy | Whole pregnancy | |||||
| 0.4 FA (n = 4321) | MV + 0.4 FA (n = 831) | MV + 0.8 FA (n = 2309) | 0.4 FA (n = 838) | MV + 0.4 FA (n = 418) | MV + 0.8 FA (n = 917) | ||
| HDCP | |||||||
| Crude RR (95% CI) | 1 | 0.71(0.49-1.05) | 0.75 (0.44-1.28) | 0.42 (0.27-0.68) | 0.64(0.36-1.12) | 0.68 (0.33-1.37) | 0.49 (0.27-0.89) |
| P | 0.084 | 0.294 | 0.001 | 0.120 | 0.279 | 0.019 | |
| Model RR (95% CI) | 1 | 0.82(0.55-1.20) | 0.93 (0.54-1.61) | 0.49 (0.31-0.80) | 0.77(0.43-1.35) | 0.80 (0.39-1.65) | 0.62 (0.34-1.15) |
| P | 0.305 | 0.789 | 0.004 | 0.358 | 0.553 | 0.128 | |
|
| |||||||
| Preeclampsia | |||||||
| Crude RR (95% CI) | 1 | 0.52(0.28-0.99) | 0.70 (0.29-1.69) | 0.09 (0.03-0.33) | 0.44(0.16-1.21) | 0.70 (0.23-2.14) | 0.40 (0.14-1.11) |
| P | 0.046 | 0.431 | 0.001 | 0.111 | 0.531 | 0.077 | |
| Model RR (95% CI) | 1 | 0.61(0.32-1.16) | 0.88 (0.36-2.16) | 0.11 (0.03-0.39) | 0.53(0.19-1.49) | 0.84 (0.27-2.62) | 0.53 (0.19-1.50) |
| P | 0.132 | 0.787 | 0.001 | 0.227 | 0.766 | 0.23 | |
Crude: without adjusting for any covariates. Model: adjusted for education, prepregnancy BMI, age, weight gain during pregnancy, ethnicity, infant gender, and primiparity. FA: folic acid, 0.4 FA: 0.4 mg folic acid, MV + 0.4 FA: multivitamins with 0.4 mg folic acid, MV + 0.8 FA: multivitamins with 0.8 mg folic acid. ∗P < 0.05.