Table 4.
Regression analysis of FA supplementation and HDCP and preeclampsia (0.4FA group as reference).
| Early pregnancy (n = 7461) | Whole pregnancy (n = 2173) | |||||
|---|---|---|---|---|---|---|
| 0.4 FA (n = 5177) | MV + 0.4 FA (n = 1274) | MV + 0.8 FA (n = 3183) | 0.4 FA (n = 5177) | MV + 0.4 FA (n = 1274) | MV + 0.8 FA (n = 3183) | |
| HDCP | ||||||
| Crude RR(95% CI) | 1 | 1.05 (0.66-1.67) | 0.60 (0.41-0.87) | 1 | 0.95 (0.49-1.82) | 0.67 (0.40-1.17) |
| P | 0.834 | 0.008 | 0.871 | 0.163 | ||
| Model RR(95% CI) | 1 | 1.12 (0.70-1.79) | 0.60 (0.41-0.88) | 1 | 0.98 (0.50-1.90) | 0.77 (0.45-1.31) |
| P | 0.635 | 0.009 | 0.942 | 0.337 | ||
|
| ||||||
| Preeclampsia | ||||||
| Crude RR(95% CI) | 1 | 1.35 (0.62-2.94) | 0.18 (0.06-0.60) | 1 | 1.34 (0.47-3.81) | 0.76 (0.29-1.96) |
| P | 0.457 | 0.005 | 0.586 | 0.568 | ||
| Model RR(95% CI) | 1 | 1.42 (0.65-3.12) | 0.18 (0.06-0.59) | 1 | 1.38 (0.48-3.95) | 0.85 (0.33-2.20) |
| P | 0.381 | 0.005 | 0.551 | 0.735 | ||
Crude: without adjusting for any covariates. Model: adjusted for education, prepregnancy BMI, age, weight gain during pregnancy, ethnicity, infant gender, and primiparity. FA: folic acid, 0.4 FA: 0.4 mg folic acid, MV + 0.4 FA: multivitamins with 0.4 mg folic acid, MV + 0.8 FA: multivitamins with 0.8 mg folic acid. ∗P < 0.05.