Figure 3.

Freedom from heart failure hospitalization based on the integration of flow/mass ratio and mid-range ejection fraction (40–50% vs. ≥50%). Kaplan–Meier survival curves are shown for heart failure hospitalization with patients characterized by preserved vs. mid-range ejection fraction (ejection fraction > 50% vs. ejection fraction 40–50%) and preserved vs. low Flow/Mass ratio (≥ vs. <sex-specific median). Patients with both mid-range ejection fraction and low flow/mass ratio have the worst heart failure hospitalization prognosis. The displayed hazard ratio is derived from the Cox proportional hazards model, adjusted for age, sex, body mass index, history of diabetes, radiotracer, estimated glomerular filtration rate, and number of antihypertensive medications. CI, confidence interval; EF, ejection fraction; HF, heart failure; HR, hazard ratio.