Extended Data Fig. 10. Immunofluorescence characterization of BCOR-mut and BCOR-wt at different neural differentiation stages.

a, At the hiPSC stage, BCOR-mut colonies are indistinguishable from BCOR-mut, both expressing SSEA4 (green) and OCT4/POU5F1 (red). b,c, BCOR-mut cells have impaired neural differentiation resulting in fewer Pax 6 positive cells at Day 12 (b) and TUBB3 positive cells at Day 27 (c).