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. 2022 Aug 22;54(9):1345–1354. doi: 10.1038/s41588-022-01158-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — The genetic correlations were computed with LD score regression. The change in absolute genetic correlation is shown to visualize the change in the strength of the genetic relationships with educational attainment or household income (the directions of the genetic correlations vary between traits and are displayed in Extended Data Figs. 3 and 4). Error bars indicate 95% confidence intervals. Asterisks indicate FDR-corrected P < 0.05, corresponding to a significant change in genetic correlation. Sample sizes of the GWASs ranged from 63,780 to 254,387 (see Supplementary Table 1 for sample size per trait).