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. 2022 Aug 22;54(9):1345–1354. doi: 10.1038/s41588-022-01158-0

Extended Data Fig. 1. Results of sibling educational attainment polygenic score analyses for 56 complex traits.

Extended Data Fig. 1

Sample sizes range from 11,093 to 43,516, see Supplementary Table 1 for sample size per trait. Panel a shows the comparison between the individual-level effect estimate of model 1 and the within-family effect estimate from model 2. Panel b shows the comparison between the between-family effect estimate of model 2 and the between-family effect estimate from model 4. A total of 38 traits showed a significant decrease (FDR-corrected P value of the difference based on 1000 bootstraps), of which the top five are: household income (p = 1.6 × 10−103), educational attainment (p = 1.6 × 10−83), time spent watching TV (p = 4 × 10−61), body fat (p = 7 × 10−43) and BMI (p = 5 × 10−40).