Table 1.
Ovarian cancer patient characteristics by extreme quintiles of pre- and post-diagnosis empirical dietary inflammatory pattern (EDIP) score and Alternative Healthy Eating Index (AHEI), NHS and NHSII.
| EDIP score | AHEI | |||||||
|---|---|---|---|---|---|---|---|---|
| Pre-diagnosis questionnaire | Post-diagnosis questionnaire | Pre-diagnosis questionnaire | Post-diagnosis questionnaire | |||||
| Quintile 1 n = 200 | Quintile 5 n = 200 | Quintile 1 n = 156 | Quintile 5 n = 156 | Quintile 1 n = 200 | Quintile 5 n = 200 | Quintile 1 n = 139 | Quintile 5 n = 139 | |
| Diet score, median | −0.36 | 0.34 | −0.41 | 0.36 | 39.7 | 65.6 | 40.4 | 71.8 |
| Deaths from ovarian cancer, n (%) | 128 (64) | 109 (55) | 74 (47) | 82 (53) | 122 (61) | 120 (60) | 72 (52) | 64 (46) |
| Deaths from all causes, n (%) | 142 (71) | 123 (62) | 91 (58) | 101 (65) | 134 (67) | 141 (71) | 87 (63) | 78 (56) |
| Age at diagnosis, years, median (IQR) | 66 (56–73) | 61 (52–70) | 60 (52–68) | 59 (50–67) | 61 (52–68) | 66 (57–74) | 60 (51–68) | 61 (52–69) |
| Calendar year of diagnosis, years, median (IQR) | 2002 (1995–2007) | 2002 (1996–2008) | 2001 (1995–2006) | 1999 (1994–2006) | 2001 (1995–2007) | 2004 (1998–2008) | 1997 (1992–2003) | 2005 (1999–2009) |
| Overall survival time, years, median (IQR) | 3.7 (1.7–8.5) | 5.6 (2.1–11.7) | 6.8 (3.7–14.9) | 7.0 (3.9–14.3) | 4.5 (1.8−8.2) | 3.7 (1.7–9.0) | 7.3 (4.2–16.3) | 6.2 (4.3–11.9) |
| Stage, n (%) | ||||||||
| I | 41 (21) | 53 (27) | 43 (28) | 45 (29) | 46 (23) | 48 (24) | 38 (27) | 41 (30) |
| II | 15 (8) | 21 (11) | 12 (8) | 18 (12) | 26 (13) | 15 (8) | 17 (12) | 12 (9) |
| III | 144 (72) | 126 (63) | 101 (65) | 93 (60) | 128 (64) | 137 (69) | 84 (60) | 86 (62) |
| Histotype, n (%) | ||||||||
| High-grade serous or poorly differentiated | 140 (70) | 108 (54) | 101 (65) | 88 (56) | 115 (58) | 129 (65) | 91 (65) | 91 (65) |
| Mucinous | 6 (3) | 6 (3) | 3 (2) | 5 (3) | 11 (6) | 4 (2) | 4 (3) | 2 (1) |
| Endometrioid | 21 (11) | 40 (20) | 23 (15) | 35 (22) | 38 (19) | 25 (13) | 29 (21) | 18 (13) |
| Clear cell | 14 (7) | 13 (7) | 13 (8) | 9 (6) | 12 (6) | 16 (8) | 7 (5) | 14 (10) |
| Other or unknown | 19 (10) | 33 (17) | 16 (10) | 19 (12) | 24 (12) | 26 (13) | 8 (6) | 14 (10) |
| Body mass index, kg/m2, median (IQR) | 24.0 (22.3–26.9) | 28.3 (23.6–33.1) | 24.0 (21.8–27.1) | 27.4 (23.4–31.9) | 27.0 (22.9–33.0) | 24.2 (22.2–28.2) | 25.8 (22.3–30.7) | 24.4 (21.5–28.2) |
| Ever smoker, n (%) | 123 (62) | 81 (41) | 89 (57) | 79 (51) | 89 (45) | 108 (54) | 73 (53) | 71 (51) |
| Current NSAIDs use, n (%) | 117 (59) | 111 (56) | 81 (52) | 79 (51) | 117 (59) | 116 (58) | 72 (52) | 80 (58) |
IQR interquartile range, NHS Nurses’ Health Study; NHSII, Nurses’ Health Study II, NSAID non-steroidal anti-inflammatory drug.