Table 4.

Change in dietary patterns from pre-diagnosis to post-diagnosis and mortality among women with ovarian cancer, NHS and NHSII.

		Ovarian cancer specific mortality		All-cause mortality
	Total cases, n	Deaths, n	HR (95% CI)	Deaths, n	HR (95% CI)
EDIP score
Low–Low	257	132	ref	157	ref
Low–High	98	54	1.38 (0.99–1.92)	66	1.44 (1.06–1.95)
High–Low	98	45	1.07 (0.71–1.61)	57	1.16 (0.79–1.68)
High–High	257	138	1.58 (1.09–2.30)	166	1.55 (1.10–2.19)
AHEI
Low–Low	229	117	ref	142	ref
Low–High	81	37	1.04 (0.71–1.53)	41	0.97 (0.68–1.39)
High–Low	81	43	0.92 (0.60–1.43)	52	0.89 (0.60–1.32)
High–High	230	116	1.10 (0.71–1.70)	143	1.08 (0.73–1.60)

EDIP score and AHEI were dichotomized at the median. Low–Low, the reference category, represents participants who persistently consumed low EDIP score diet or AHEI (below the median) from pre- to post-diagnosis period.

Models were adjusted for age at diagnosis, calendar year at diagnosis, histology, stage, smoking status, body mass index (<25, 25–29, 30+), total energy intake, nonsteroidal anti-inflammatory drug (NSAID) use, pre-diagnosis cumulative average EDIP score or AHEI.

AHEI alternative healthy eating index, CI confidence interval, EDIP empirical dietary inflammatory pattern score, HR hazard ratio, NHS Nurses’ Health Study, NHSII Nurses’ Health Study II, p-het p-heterogeneity.