TABLE 1.

Occurrence of known and prospective isoprenoid pathway genes in members of the Bacteria, Archaea, and Eucaryota

Genea	Bacteria																			Archaea						Eucaryota
	Aquifex aeolicus	Synechocystis strain PCC 6803	Mycobacterium tuberculosis	Bacillus subtilis	Mycoplasma genitalium	Mycoplasma pneumoniae	Ureaplasma urealyticum	Chlamydia pneumoniae	Chlamydia trachomatis	Rickettsia prowazekii	Neisseria meningitidis	Campylobacter jejuni	Helicobacter pylori	Haemophilus influenzae	Escherichia coli	Borrelia burgdorferi	Treponema pallidum	Thermatoga maritina	Deinococcus radiodurans	Aeropyrum pernix	Archaeoglobus fulgidus	Methanobacterium thermoautotrophicum	Methanococcus jannaschii	Pyrococcus abyssi	Pyrococcus horikoshii	Saccharomyces cerevisiae	Arabidopsis thaliana	Homo sapiens
dxs	+	+	+	+				+	+		+	+	+	+	+		+	+	+								+
dxr	+	+	+	+				+	+		+	+	+	+	+		+	+	+								+
ygbB	+	+	+	+				+	+		+	+	+	+	+		+	+	+								+
ygbP	+	+	+	+				+	+		+	+	+	+	+		+	+	+						+		+
ychB	+	+	+	+			+		+		+	+	+	+	+		+	+	+								+
lytBb	+	+	+	+				+	+		+	+	+	+	+		+	+	+								+
gcpEb	+	+	+	+				+	+		+	+	+	+	+		+	+	+								+
ipi			+												+											+	+	+
hmgr																+				+	+	+	+	+	+	+	+	+
mvk																+				+	+	+	+	+	+	+	+	+
pmk																+										+	+	+
mvd																+										+	+	+

^amvk, mevalonate kinase gene; pmk, phosphomevalonate kinase gene; mvd, mevalonate diphosphate decarboxylase gene. 

^bGenes of unknown function with a genomic distribution consistent with a role in the DOXP pathway.