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. 2022 Aug 31;13:921837. doi: 10.3389/fgene.2022.921837

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Copyright © 2022 Lai, Yang, Chu, Xu and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction of a prognostic model for stage I–III LUSC patients according to three CSRGs. (A) Identifying 12 prognostic CSRGs using univariate Cox regression analysis. (B) Principal component analysis (PCA) based on the expression levels of three CSRGs in the TCGA training set. (C) Distribution of risk scores, survival status, and three CSRG expression panels in the training set. (D) Kaplan–Meier survival analysis of OS between the high-risk and low-risk groups. (E) Time-dependent ROC for 1-, 3-, and 5-year OS predictions for the CSRG prognostic signature in the training set.