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. 2022 Aug 27;21(9):e13683. doi: 10.1111/acel.13683

FIGURE 1.

FIGURE 1

SBP and DBP in mmHg comparison among WT groups treated either with vehicle, low dose (80 mg/kg/day) or high dose (200 mg/kg/day) of the sGC activator BAY 54–6544 (a). The amount of the chow consumption in WT mice receiving either vehicle chow or chow containing 80 mg/kg/day or 200 mg/kg/day of BAY 54–6544 (b). Survival rate at the end of the study in WT and Ercc1 Δ/− treated either with vehicle or BAY 54–6544 (c). Body weight changes in WT and Ercc1 Δ/− treated either with vehicle or BAY 54–6544 (200 mg/kg/d) during 8 weeks of treatment (d). Data are presented in mean ± SEM. Statistical differences were analyzed by one‐way ANOVA followed by Dunnett's post hoc test for A and B and log‐rank (Mantel‐Cox) test for C (* = p < 0.05). And by general linear model repeated measures for D