FIGURE 2.

SBP (a) and DBP (b) in mmHg in WT and Ercc1 ^Δ/− treated either with vehicle or BAY 54–6544 (200 mg/kg/d). Functional differences between skin reperfusion after 2 minutes of occlusion in calculated area under the curve (AUC) (c) and average maximum response (max response) (d) in WT and Ercc1 ^Δ/− treated either with vehicle or BAY 54–6544. Data are presented in mean ± SEM. Statistical differences were analyzed by two‐way ANOVA followed by Bonferroni's post hoc test (* = p < 0.05)