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. 2022 Aug 18;21(9):e13692. doi: 10.1111/acel.13692

FIGURE 6.

FIGURE 6

B cells from aged donor mice preferentially localize to the extrafollicular compartment early in the immune response. Confocal images of spleens of recipient mice taken 6 days post‐transfer of B cells from 5 or 97 weeks old SWHEL donor mouse and HEL–SRBC immunisation. 10 μm spleen sections were stained with anti‐CD45.2 (green), anti‐HEL (red), anti‐IgD (blue) and anti‐CD3 (white) antibodies and imaged at 20× to look at the localisation of transferred cells in the (a) extrafollicular compartment and the (b) germinal centre. Data were representative of two independent repeat experiments.