TABLE 2.

Intergroup comparisons of cortical thickness in different brain regions.

Brain region	Cluster size	MNI coordinates			Vertices	P
		X	Y	Z
Cortex thinner in PD-MDD than in HC
Left fusiform gyrus	4169.65	−34.7	−33.7	−25.2	7379	<0.0001
Left pars opercularis	855.30	−41.3	26.6	13.6	1336	0.0002
Right fusiform gyrus	2202.52	33.1	−45.9	−14.2	4054	<0.0001
Right temporal pole	1342.82	30.5	2.4	−29.6	2334	0.0001
Right middle temporal	1329.78	53.2	−12.6	−21.0	2353	<0.0001
Right lateral orbitofrontal	1094.30	34.2	33.6	−8.2	2118	0.0002
Right lateral occipital	830.12	33.7	−88.9	−6.1	1055	<0.0001
Right post-central	778.46	46.9	−18.1	55.7	1556	<0.0001
Cortex thinner in PD-MDD than in PD-MnD
Left fusiform gyrus	2781.41	−32.4	−45.5	−15.0	4777	<0.0001
Right fusiform gyrus	1232.61	32.0	−49.5	−17.1	2197	<0.0001
Cortex thinner in PD-MDD than in PD-ND
Left fusiform gyrus	4298.42	−30.7	−57.1	−12.1	6354	<0.0001
Left lateral occipital cortex	1101.50	−28.3	−90.9	−3.3	1460	0.0005
Left superior temporal gyrus	726.48	−41.2	−17.7	−10.5	1874	0.0001
Left lateral orbitofrontal cortex	713.69	−29.6	28.1	−16.6	1367	0.0007
Right fusiform gyrus	3785.34	33.3	−51.2	−6.6	5349	0.0003
Right middle temporal gyrus	1614.58	50.9	−13.6	−20.1	2641	<0.0001
Right RMFG	1042.61	37.5	33.1	10.5	1735	0.0002
HAMD correlation
Left fusiform gyrus	1954.98	−31.3	−68.7	−14.9	2507	0.0001
Left lingual gyrus	907.86	−9.1	−73.4	−2.6	1499	0.0002
Right lateral occipital cortex	1367.21	21.6	−93.8	−9.5	1691	<0.0001

HAMD, Hamilton Rating Scale for Depression; HC, healthy controls; MNI, Montreal Neurological Institute; PD, Parkinson’s disease; PD-ND, non-depressed PD patients; PD-MnD; PD patients with minor depression; PD-MDD, PD patients with major depressive disorder; RMFG, rostral middle frontal gyrus.