TABLE 3.
Intergroup comparison of functional connectivity in different brain regions.
ROI [MNI coordinates (X, Y, Z)] | Brain regions | MNI coordinates | Vertices | T value | ||
|
||||||
X | Y | Z | ||||
FC difference when PD-MDD minus HC | ||||||
Left pars opercularis (−41.3, 26.6, 13.6) |
Right midbrain limbic lobe | 3 | −30 | −15 | 327 | −4.0879 |
Right fusiform gyrus (33.1, −45.9, −14.2) |
Left parietal lobe | −45 | −54 | 42 | 476 | −4.4103 |
Limbic lobe cingulate gyrus |
−6 | −24 | 42 | 360 | −4.2659 | |
Right middle temporal gyrus (53.2, −12.6, −21.0) |
Bilateral occipital lobe Right cerebrum |
18 | −102 | −9 | 1328 | −5.4053 |
Right lateral orbitofrontal cortex (34.2, 33.6, −8.2) |
Right cerebellum | 24 | −51 | −54 | 528 | 4.1848 |
Right lateral occipital cortex (33.7, −88.9, −6.1) |
Right temporal lobe | 54 | −27 | −9 | 463 | −4.5896 |
FC difference when PD-MDD minus PD-ND | ||||||
Left superior temporal gyrus (−41.2, −17.7, −10.5) |
Right cerebellum posterior lobe | 33 | −60 | −21 | 447 | −4.5084 |
Right RMFG (37.5, 33.1, 10.5) |
Right inferior frontal gyrus Right insula |
63 | 12 | 0 | 707 | −4.502 |
HC, healthy controls; MNI, Montreal Neurological Institute; PD, Parkinson’s disease; PD-ND, non-depressed PD patients; PD-MnD, PD patients with minor depression; PD-MDD, PD patients with major depressive disorder; RMFG, rostral middle frontal gyrus; ROI, region of interest.