Table 2.

Model parameter estimates and ranges

Parameter	Base-case parameters	Sensitivity analysis	Source
Infection fatality ratio (IFR) for pre-Omicron COVID-19	5/1000		Levin et al23
IFR for Omicron variant of COVID-19	1/1000	5/10 000 5/1000	Levin et al23 Lewnard et al25 Abdullah et al13
Natural immunity protection against COVID-19 mortality	80%		Bozio et al24
Vaccine effectiveness against COVID-19 mortality, two dose	80%	80% 95%	Sheikh et al31
Vaccine effectiveness against COVID-19 mortality, two dose+booster	90%	90% 99%	Sheikh et al31
Cost per vaccine dose administered	US$7	US$5–US$10	Public Citizen15 WHO16