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. 2022 Aug 31;13:900963. doi: 10.3389/fimmu.2022.900963

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Copyright © 2022 Zhang, Yuan, Li, Luo, Zhou, Yu and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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EVs-DexP inhibits lymphocytes activation in vitro. (A) Flow cytometry analysis of CD4⁺CD69⁺ population after the DexP or EVs-DexP treatment of PPs lymphocytes activated by ConA. From left to right, living cells, CD3⁺ cells, CD4⁺CD69⁺cells are detected. (B) CCK-8 assay showing the effect of EVs, DexP and EVs-DexP on PPs lymphocyte proliferation after co-culture for 24h. Data are presented as mean ± SD, * p<0.05 vs. ConA+EVs, *** p<0.001 vs. ConA+EVs, # p<0.05 vs. ConA+DexP; one-way ANOVA.