FIGURE 4.

Effect of G-Rh4 on RAW264.7 cells. (A) Effect of G-Rh4 on cell viability. Cells were treated with different concentrations of G-Rh4 for 24 h. (B–D) Production of IL-6, TNF-α, and IL-1β in LPS-stimulated RAW264.7 cells was determined by ELISAs. (E–G) Effect of G-Rh4 on TNF-α, IL-6, and IL-1β mRNA levels in RAW264.7 cells. Data were presented as the mean ± SD values performed in triplicate (^## p < 0.01 and ^### p < 0.001 vs. control group, *p < 0.05, **p < 0.01, ***p < 0.001 vs. LPS group).