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. 2022 Aug 31;13:957245. doi: 10.3389/fendo.2022.957245

Figure 2.

Figure 2

Histological analysis of atrial fibrosis in patient biopsies. Representative images of atrial fibrosis in NoMAFLD patient (A); MAFLD w/o fibrosis (B); MAFLD w/severe fibrosis (C). Red arrows indicate fibrotic foci. Semi-automatic quantification: ratio between positive fibrotic area and total selected area (D). NoMAFLD: FLI < 60; MAFLD w/o fibrosis: FLI > 60 and NFS < 1.455; MAFLD w/severe fibrosis: FLI > 60 and NFS > 0.675. Kruskal–Wallis test followed by Dunn’s post-hoc test. *p < 0.05. MAFLD, metabolic dysfunction-associated fatty liver disease.