Table 1.
Baseline characteristics According to MAFLD status.
| noMAFLD (n = 123) | MAFLD (n=122) | P | |
|---|---|---|---|
| Criteria | FLI<60 | FLI≧60 | |
| Age (years) | 60.3±10.2 | 58.1±9.9 | 0.089 |
| Women, n (%) | 56 (46%) | 29 (23%) | 0.0004 |
| BMI (kg/m²) | 24.7±3.0 | 31.4±4.5 | <0.0001 |
| Chronic alcohol consumption, n (%) | 9 (7%) | 22 (18%) | 0.023 |
| Waist circumference (cm) | 91.3±9.6 | 112.0±12.1 | <0.0001 |
| Hypertension, n (%) | 36 (29%) | 68 (55%) | 0.0001 |
| Diabetes mellitus, n (%) | 15 (12%) | 27 (22%) | 0.067 |
| CHa2DS2Vasc | 1 [1;3] | 2 [1;3] | 0.409 |
| Paroxysmal AF, n (%) | 72 (59%) | 51 (41%) | 0.004 |
| Persistent AF, n (%) | 51 (41%) | 69 (56%) | |
| PVI alone, n (%) | 100 (83%) | 92 (79%) | 0.536 |
| PVI + lines, n (%) | 21 (17%) | 25 (21%) | |
| AAD at discharge | 22 (17.9%) | 34 (27.8%) | 0.0789 |
| Flecainide | 12 (55%) | 13 (38%) | |
| Sotalol | 4 (18%) | 4 (12%) | |
| Amiodarone | 6 (27%) | 17 50%) | |
| History of heart failure, n (%) | 24 (20%) | 37 (30%) | 0.083 |
| LVEF – normal range, n (%) | 58 (48%) | 38 (31%) | 0.0075 |
| LVEF – mildly abnormal range, n (%) | 60 (50%) | 76 (61%) | |
| LVEF – abnormal range, n (%) | 3 (2%) | 10 (8%) | |
| Left atrium area (cm²) | 23 [19;26] | 28 [24;31] | <0.0001 |
| Fasting glucose (mg/dl) | 98±15 | 108±18 | <0.0001 |
| HOMA IR | 1.34 [0.89;2.06] | 2.45 [1.65;3.45] | <0.0001 |
| Triglycerides (g/l) | 90 [72;116] | 137 [106;182] | <0.0001 |
| ASAT (UI/l) | 23 [18;26] | 24 [18;30] | 0.0274 |
| ALAT (UI/l) | 20 [16;26] | 27 [21;37] | <0.0001 |
| Gamma GT (UI/l) | 24 [18;34] | 47 [32;86] | <0.0001 |
| Albumin (g/l) | 38 [36;42] | 39 [36;42] | 0.906 |
| Nt pro BNP (ng/l) | 209 [97;487] | 294 [115;659] | 0.198 |
Statistics, for continuous variables with normal distribution, Student’s t-test; for continuous variables without normal distribution, Mann-Whitney U test; for frequencies, chi-squared test; for frequencies with linear trends (AF subtype; PVI ± other lines; LVEF) chi-squared for trend. MAFLD, Metabolic-dysfunction Associated Fatty Liver Disease; BMI, Body Mass Index; AF, Atrial Fibrillation; PVI, Pulmonary Vein(s) Isolation; AAD, Anti-Arrhythmic Drug; LVEF, Left Ventricular Ejection Fraction; FLI, Fatty Liver Index. Norms, chronic alcohol consumption >40 g per day in men, and >20 g per day in women 28; LVEF normal range ≥ 50%; mildly normal range 41%–49%; normal range ≤ 40% 29.
P-values lower than 0.05 are represented in bold.