Figure 1.

PRISMA flowchart for study selection. On the basis of our preset eligibility criteria, 2083 abstracts were reviewed. From these, 479 underwent full text review, leading to 28 studies that were included for our aggregate data meta-analysis and 24 studies with available individual patient data. MeSH, Medical Subject Headings; PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses.