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Grading of burden of cerebral small vessel disease (CSVD) by: grading of white matter hyperintensities (WMH) according to Fazekas scale for periventricular hyperintensities (PVH, 0–3) and deep WMH (DMWH, 0–3); total CSVD burden (0–4); and the Microbleed Anatomical Rating Scale (MARS) for cerebral microbleeds (CMB) (sum of definite and probable)
| Scoring system | MRI 1 month | MRI 7 months |
| Fazekas PVH | 2 | 3 |
| Fazekas DMWH | 2–3 | 3 |
| CSVD burden | 2 | 3 |
| MARS (CMB) | 16 | 17 |
