Table 3.
Association between phthalate metabolites and type 2 diabetes in Sun et al. (2014).
| Phthalate (metabolite) | NHS OR (95% CI) | NHSII OR (95% CI) | Pooled OR (95% CI) for Q4 vs. Q1 |
|---|---|---|---|
|
| |||
| DEHP (summed metabolites) | ∑DEHP | ∑DEHP | MEOHP |
| Q2: 0.88 (0.52,1.50) | Q2: 1.80 (1.07,3.04) | 1.42 (0.95,2.11) | |
| Q3: 1.02 (0.61,1.71) | Q3: 1.62 (0.95,2.76) | ||
| Q4: 1.34 (0.77,2.30) | Q4: 1.91 (1.04,3.49) | ||
| Ptrend=0.1 | Ptrend=0.2 | ||
|
| |||
| DBP+DIBP (MBP+MIBP) | Q2: 1.26 (0.75,2.12) | Q2: 1.38 (0.81,2.35) | n/a |
| Q3: 1.01 (0.59,1.73) | Q3: 1.17 (0.66,2.10) | ||
| Q4: 0.91 (0.50,1.68) | Q4: 3.16 (1.68,5.95) | ||
| Ptrend=0.5 | Ptrend=0.0002 | ||
|
| |||
| DBP (MBP) | n/a | Q2: 1.53 (0.90,2.61) | n/a |
| Q3: 1.18 (0.67,2.09) | |||
| Q4: 3.16 (1.69,5.92) | |||
| Ptrend =0.0003 | |||
|
| |||
| DIBP (MIBP) | n/a | Q2: 1.28 (0.76,2.13) | n/a |
| Q3: 1.12 (0.62,2.02) | |||
| Q4: 2.67 (1.44,4.95) | |||
| Ptrend =0.001 | |||
|
| |||
| BBP (MBzP) | Q2: 0.91 (0.55,1.51) | Q2: 0.85 (0.50,1.44) | 0.96 (0.65,1.43) |
| Q3: 0.85 (0.51,1.40) | Q3: 1.08 (0.62,1.86) | ||
| Q4: 0.82 (0.48,1.43) | Q4: 1.14 (0.65,2.01) | ||
| Ptrend=0.5 | Ptrend=0.4 | ||
|
| |||
| DEP (MEP) | Q2: 1.13 (0.69,1.84) | Q2: 1.00 (0.60,1.67) | 0.80 (0.56,1.16) |
| Q3: 0.98 (0.60,1.61) | Q3: 0.46 (0.26,0.82) | ||
| Q4: 0.72 (0.43,1.20) | Q4: 0.91 (0.54,1.54) | ||
| Ptrend=0.09 | Ptrend=0.97 | ||
Exposure levels presented in paper as medians of each quartile.
Results that support an association are shaded. Dark grey represents one or more of the following: p < 0.05, large effect size (e.g., OR ≥1.5), or exposure-response trend. Light grey represents other supportive results.