Table 1.
OAR constraint and target volume metrics are presented for the initial non adaptive (PI) and adapted (PA) plans
| Organ-at-risk | Strict constraint | PI mean (std dev) | PI median (range) | PA mean (std dev) | PA median (range) |
|---|---|---|---|---|---|
| Stomach | V25 Gy < 0.5 cc (cc) | 10.2 (3.6) | 9.7 (5.6–14.8) | 0.0 (0.1) | 0.0 (0.0–0.1) |
| Duodenum | V25 Gy < 0.5 cc (cc) | 0.1 (0.1) | 0.1 (0.0–0.2) | 0.0 (0.0) | 0.0 (0.0–0.0) |
| Small bowel | V25 Gy < 0.5 cc (cc) | 3.8 (5.1) | 1.2 (0.3–13.8) | 0.0 (0.0) | 0.0 (0.0–0.1) |
| Large bowel | V25 Gy < 0.5 cc (cc) | 0.0 (0.0) | 0.0 (0.0–0.1) | 0.1 (0.1) | 0.0 (0.0–0.2) |
| Liver | V25 Gy < 33% (%) | 9.5 (1.6) | 10.1 (6.8–11.4) | 12.1 (1.8) | 11.0 (10.3–14.7) |
| 700 cc < 20 Gy (Gy) | 0.4 (.1) | 0.3 (0.2–0.6) | 0.4 (0.1) | 0.4 (0.3–0.5) | |
| Mean < 20 Gy (Gy) | 1.0 (0.2) | 1.0 (0.8–1.2) | 1.2 (0.1) | 1.2 (1.0–1.3) | |
| Spinal cord | V25 Gy < 0.5 cc (cc) | 0.0 (0.0) | 0.0 (0.0–0.0) | 0.0 (0.0) | 0.0 (0.0–0.0) |
| Kidneys (both) | Mean < 18 Gy (Gy) | 0.8 (0.7) | 0.8 (0.7–0.9) | 0.8 (0.1) | 0.8 (0.7–0.9) |
| Target volume | Coverage goal | PI mean (std dev) | PI median (range) | PA mean (std dev) | PA median (range) |
|---|---|---|---|---|---|
| PTV V100 | N/A (%) | 77.1 (2.1) | 76.0 (74.5–80.0) | 77.8 (5.1) | 80.8 (67.9–81.3) |
| PTV D95 | N/A (Gy) | 4.7 (0.1) | 4.6 (4.6–4.9) | 4.8 (0.1) | 4.8 (4.6–5.0) |
| PTVopt | 95% (%) | 83.5 (3.8) | 83.5 (78.8–91.4) | 99.6 (0.3) | 99.5 (99.2–100.1) |
| GTV V100 | N/A (%) | 89.9 (1.1) | 90.0 (88.5–91.4) | 90.0 (4.0) | 91.8 (82.2–93) |
| GTV D95 | N/A (Gy) | 6.0 (0.2) | 6.1 (5.6–6.3) | 6.4 (0.3) | 6.5 (5.7–6.7) |
Mean and median constraint and target metrics for the PI represent the hypothetical use of the PI applied to all five fractions
N/A not applicable, Std Dev standard deviation