FIG 3.

The effect of testosterone on the frequency and number of dendritic cells following oral CVB3 inoculation. (A) Representative flow cytometry plots of CD11c⁺, MHC II splenic dendritic cells at 5 dpi in uninfected and CVB3-infected mice that were either testosterone-treated or testosterone-depleted (placebo). The frequency (B) and number (C) of splenic dendritic cells in testosterone-treated (blue with diagonal lines) and testosterone-depleted (gray) mice following infection. *, P < 0.05, **, P < 0.01, ****, P < 0.0001; two-way ANOVA. All data are from two independent experiments with n = 4 to 6 mice per group and are shown as mean ± SEM.