TABLE 1.

The frequency and number of characterized splenocytes from uninfected and infected testosterone-depleted (placebo) or testosterone-treated (testosterone) mice^a,b

	Uninfected male mice				CVB3-infected male mice
Infection	Frequency of cells (%) per spleen		Total no. of cells (×103) per spleen		Frequency of cells (%) per spleen		Total no. of cells (×103) per spleen
Cell type	Placebo	Testosterone	Placebo	Testosterone	Placebo	Testosterone	Placebo	Testosterone
Total Splenocytes	100	100	51375 ± 5134.57*	29250 ± 2721.57*	100	100	33166.667 ± 2216.10*	21200 ± 2527.85*
Macrophages	1.62 ± 0.10	2.55 ± 0.35	840.0 ± 114.8	653.8 ± 51.15	1.55 ± 0.15	2.08 ± 0.32	451.9 ± 90.6	521.8 ± 79.4
Monocytes	0.7538 ± 0.13	0.7111 ± 0.06	402.763 ± 102.02	197.672 ± 25.17	0.783 ± 0.08	1.07 ± 0.17	258.3 ± 27.4	218.1 ± 29.3
Neutrophils	0.435 ± 0.09	1.25 ± 0.36	205.025 ± 41.35	306.4 ± 74.07	0.2 ± 0.06	0.374 ± 0.08	66.4 ± 20.6	84.1 ± 21.5
B cells	58.86 ± 1.76*	45.72 ± 3.95*	30553.875 ± 3730.96*	12776.25 ± 1380.84*	58.18 ± 2.05*	41.3 ± 2.73*	19592 ± 1434.7*	8 928.4 ± 1329.4*

^aData are presented as mean +/– SEM from two independent experiments (n = 5 to 6 per group).

^bStatistically significant differences between groups are bolded and denoted by asterisks (*, P < 0.05).