Table 1.
Summary of experiments using pseudotyped reporter virions.
| Treatment | Number of embryos tested | Embryos with fluorescent cells |
|---|---|---|
| HIV-based reporter | ||
| No treatment | 15 | 0 |
| No pseudotype (‘Bald’) virus | 15 | 0 |
| SARS-CoV-2 S pseudotyped virus | 15 | 6 (40%) |
| SARS-CoV-2 S pseudotyped virus + anti-S neutralizing antibody | 7 | 1 (14.3%) with limited puncta |
| VSV∆G -based reporter | ||
|---|---|---|
| No treatment | 4 | 0 |
| No pseudotype (‘Bald’) virus | 5 | 0 |
| SARS-CoV-2 S pseudotyped virus | 7 | 4 (57.1%) |
| SARS-CoV-2 S pseudotyped virus + anti-S neutralizing Antibody | 4 | 0 |
| SARS-CoV-2 S pseudotyped virus + anti-ACE2 neutralizing antibody | 4 | 2 (50%) with limited puncta |
| SARS-CoV-2 S pseudotyped virus + anti-IgG neutralizing Antibody | 6 | 4 (66.7%) |
| SARS-CoV-1 S pseudotyped virus | 5 | 4 (80%) |
| MERS-CoV S pseudotyped virus | 5 | 0 |
For each reporter virion (HIV- or VSV∆G -based), the table indicates the experimental condition, the number of embryos used, and the number/percent of infected embryos as evidenced by GFP signal.