Table 1.

Antiproliferative activity (IC₅₀) values of monensin (MON) and its analogs.

Compound	IC50 [nm]
MON	612.6 ± 184.4&
1	291.7 ± 68.8 **
2	189.8 ± 79.3 **
3	604.9 ± 149.6
4	168.7 ± 82.2**
5	487.6 ± 161.2
6	622.7 ± 203.8
7	994.9 ± 330.3
8	257.3 ± 135.6 *
9	100.0 ± 92.0 ***
10	808.3 ± 103.4
11	139.0 ± 105.4 **
12	91.5 ± 54.4 ***
13	424.0 ± 288.6
14	337.0 ± 217.1

IC₅₀ value is defined as the concentration of the compound which induces 50% growth inhibition.

Values are given as mean ± SD (n = 4 each).

^&The value is an average from two independent experiments (n = 4 each).

^*p ≤ 0.05,

^**p ≤ 0.01,

^***p ≤ 0.001.