TABLE 1.
Clinical diagnosis | Case | Brain region | Sex | Age of death (years) | PMI | Brain weight (grams) | CDR | NIA-AA ABC scores |
---|---|---|---|---|---|---|---|---|
| ||||||||
Alzheimers disease | 1 | MFG/ITG | F | 64 | 7.3 | 870 | 3 | A3, B3, C3 |
2 | MFG/ITG | M | 59 | 9 | 1,090 | 3 | A3, B3, C3 | |
3 | MFG | F | 67 | 9.7 | 1,001 | 2 | A3, B3, C3 | |
4 | MFG/ITG | M | 64 | 6.8 | 1,197 | 3 | A3, B3, C3 | |
5 | MFG | M | 71 | 6.5 | 1,029 | 3 | A3, B3, C3 | |
6 | MFG/ITG | F | 74 | 9.8 | 1,215 | 3 | A3, B3, C3 | |
7 | ITG | F | 75 | 6.9 | 1,006 | 3 | A3, B3, C3 | |
8 | MFG | M | 60 | 6.1 | 912 | 3 | A3, B3, C3 | |
Argyrophilic grain disease | 1 | MFG/ITG | F | 88 | 17.8 | 1,280 | 0.5 | A1, B2, C1 |
2 | MFG/ITG | M | 77 | 4.9 | 1,236 | 0.5 | A1, B1, C1 | |
3 | MFG/ITG | M | 87 | 6.4 | 1,225 | 0 | A1, B1, C0 | |
4 | ITG | M | 68 | 8.3 | 1,511 | 1 | A0, B2, C0 | |
Corticobasal degeneration | 1 | MFG/ITG | M | 66 | 12.1 | NA | 0.5 | A1, B1, C0 |
2 | MFG/ITG | F | 64 | 8.6 | 1,187 | 0.5 | A1, B1, C0 | |
3 | MFG/ITG | M | 73 | 8.2 | 1,192 | 3 | A1, B1, C0 | |
4 | ITG | M | 79 | 5.7 | 1,414 | 0.5 | A0, B1, C0 | |
5 | MFG | F | 64 | 7.8 | 1,132 | 0.5 | A0, B1, C0 | |
6 | MFG/ITG | F | 64 | 6.1 | 1,157 | 3 | A0, B1, C0 | |
7 | ITG | F | 63 | 5.8 | 1,023 | 1 | A1, B1, C0 | |
8 | MFG | M | 63 | 11.9 | 1,152 | 3 | A1, B1, C0 | |
9 | MFG | M | 78 | 24 | NA | 3 | A1, B1, C0 | |
10 | MFG | M | 65 | 4.5 | 1,100 | 3 | A1, B1, C0 | |
Picks disease | 1 | MFG/ITG | M | 64 | 13.7 | 1,017 | 2 | A1, B0, C0 |
2 | MFG/ITG | F | 69 | 6.3 | 1,032 | 3 | A0, B1, C0 | |
3 | MFG/ITG | M | 57 | 12.4 | 1,113 | 3 | A1, B1, C0 | |
4 | ITG | M | 60 | 15.2 | 927 | 3 | A0, B0, C0 | |
5 | MFG | F | 76 | 5.9 | 929 | 3 | A1, B0, C1 | |
6 | ITG | M | 56 | 9.2 | 990 | 3 | A1, B1, C1 | |
Progressive supranuclear palsy | 1 | MFG | F | 69 | 18.5 | 1,132 | 0.5 | A1, B1, C0 |
2 | MFG/ITG | M | 70 | 13.4 | 1,134 | 0.5 | A0, B1, C0 | |
3 | ITG | M | 68 | 10.1 | 1,250 | 0.5 | A0, B0, C0 | |
4 | MFG/ITG | F | 86 | 5.3 | 1,011 | 1 | A0, B1, C0 | |
5 | MFG/ITG | F | 68 | 13 | 1,170 | 0.5 | A1, B0, C0 | |
6 | MFG/ITG | M | 80 | 7.9 | 1,285 | 2 | A1, B1, C0 | |
7 | MFG/ITG | F | 73 | 7.1 | 1,183 | 0.5 | A2, B1, C1 | |
Control | 1 | MFG/ITG | M | 76 | 8.2 | 1,324 | 0 | A1, B1, C1 |
2 | MFG/ITG | F | 86 | 6.4 | 1,300 | 0 | A0, B1, C0 |
Abbreviations: NIA-AA, National Institute on Aging and Alzheimers Association; MFG, Middle Frontal Gyrus; ITG, Inferior Temporal Gyrus.