Table 1.
Clinical and anatomopathological characteristics found in the 321 studied individuals.
| Study Characteristic (N = 321) | No. | % |
|---|---|---|
| Age at diagnosis, years | ||
| Mean ± SD | 45,21 ± 11,22 | |
| Median | 44 | |
| Range | 26-85 | |
| ≤45 | 183 | 57.0 |
| 46-60 | 106 | 33.0 |
| >60 | 32 | 10.0 |
| Ashkenazi Jewish ethnicity | ||
| Yes | 4 | 1.2 |
| No | 317 | 98.8 |
| Breast cancer subtypes, receptor status | ||
| TNBC | 79 | 24.6 |
| HR positive/HER2 negative (Luminal) | 155 | 48.3 |
| HR negative/HER2 positive (HER2- enriched) | 13 | 4.0 |
| HR positive/HER2 positive (Luminal B HER2) | 40 | 12.5 |
| HR positive/HER2 not available | 22 | 6.8 |
| Unknown | 12 | 3.7 |
| Histology | ||
| Ductal | 265 | 82.6 |
| Lobular | 27 | 8.4 |
| Ductal and lobular | 2 | 0.6 |
| Other | 20 | 6.2 |
| Unknown | 7 | 2.2 |
| Bilateral disease | ||
| Yes | 29 | 9.0 |
| No | 292 | 91.0 |
| Patient history of second breast cancer | ||
| Yes | 38 | 11.2 |
| No | 283 | 88.2 |
| Patient history of prior cancer (excluded breast cancer) | ||
| Yes | 39 | 12.1 |
| No | 282 | 87.9 |
| Ovarian cancer | 9 | 2.8 |
| First-/second-/third- degree relative with breast or ovarian cancer | ||
| Yes | 209 | 65.1 |
| No | 106 | 33.0 |
| Unknown | 6 | 1.9 |
| First-/second-/third- degree relative with cancer (excluded breast and ovarian) | ||
| Yes | 244 | 76.0 |
| No | 71 | 22.1 |
| Unknown | 6 | 1.9 |
SD, standard deviation; TNBC, triple-negative breast cancer; HR, hormone receptor; HER2, human epidermal growth factor receptor 2.