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. 2022 Aug 31;13:952980. doi: 10.3389/fphar.2022.952980

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Copyright © 2022 Zeng, Liao, Zhou, Liu, Lin, Huang, Zhou and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of A011 on the viability of three drug-resistant cells MCF-7/ADR, A549/DDP, HepG2/DDP and their parental cells. (A) The cytotoxic effects of A011 on MCF-7/ADR, A549/DDP, HepG2/DDP and their parental cells, respectively. Cells were treated with a range of concentrations of A011, adriamycin (ADR) or cisplatin (DDP) for 24, 48 and 72 h. (B) Effect of A011 on the inhibition of clonogenic capacity of MCF-7 and MCF-7/ADR cells. Data represent mean ± SD of three different experiments. ^* p < 0.05, ^** p < 0.01 vs. Control.