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. 2022 Aug 31;13:952980. doi: 10.3389/fphar.2022.952980

FIGURE 4.

FIGURE 4

Effect of A011 on the transport function of ABCB1 and ABGC2 transporters. (A) A011 decreased the efflux of Rh123 in MCF-7/ADR cells. (B) A011 decreased the efflux of mitoxantrone in MCF-7/ADR cells. (C) A011 decreased the ATPase activity of the ABCB1 transporter. Verapamil (vera) and KO143 as a positive control group. Data represent mean ± SD of three different experiments. **p < 0.01 vs. CON.