FIGURE 2.

A, LS mean change from baseline to day 28 in STS. B, The LS mean change from baseline to day 28 in STS with missing data imputed using last available data. C, The percentage of patients with at least a 10-mm change in STS at day 28 versus baseline (intent-to-treat population) with missing data imputed using last available data. All comparisons made with the control group. No formal statistical comparisons were performed for the 0.006 mg dose versus vehicle; P values for this dose were assessed post hoc and represent nominal values. Error bars indicate CIs. The results in A are derived from a prespecified analysis and B and C are from a post hoc analysis.