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. Author manuscript; available in PMC: 2022 Dec 16.
Published in final edited form as: Cell Chem Biol. 2021 Jun 14;28(12):1758–1771.e13. doi: 10.1016/j.chembiol.2021.05.012

Table 1.

IC50 data for selected screening hits

DUB Compound IC50 ± SEM μM (n)
USP7 AV-9606–27 4.68 ± 1.05 (3)
AV-9606–41 3.83 ± 1.60 (3)
USP8 AD-10942–8 6.01 ± 0.18 (4)
USP10 Z56965384 26.6 ± 4.69 (14)
 
USP28 AV-9606–99 4.33 ± 1.08 (8)
AV-9606–129 0.402 ± 0.197 (6)
bin-01–07-07 0.046 ± 0.017 (3)
AV-11324–75 0.176 ± 0.073 (5)
USP30 AV-11324–5 0.275 ± 0.070 (6)

IC50 values for selected screening hits. Data are represented as mean ± SEM with the number of replicates for each compound (n).