Table 2. Performance characteristics of ATENEA and the endoscopists for diagnosis of adenoma.
TP | FP | TN | FN | PPV | SENS | NPV | Spec | Accuracy | |
ATENEA, n = 90 | 63 | 9 | 12 | 6 | 87.5 % (95 % CI: 78 %–94%) | 91.3 % (95 % CI: 82 %–97%) | 66.7 % (95 % CI: 41 %–87%) | 57.1 % (95 % CI: 34 %–78%) | 83.3 % (95 % CI: 74 %–90%) |
Endoscopists, n = 90 | 52 | 1 | 20 | 17 | 98.1 % (95 % CI: 90 %–100%) | 75.4 % (95 % CI: 64 %–85%) | 54.0 % (95 % CI: 37 %–71%) | 95.2 % (95 % CI: 76 %–100%) | 80.0 % (95 % CI: 70 %–88%) |
P value | 0.07 | 0.02 | 0.55 | 0.01 | 0.7 | ||||
ATENEA diminutive polyps ≤ 5 mm, n = 52 | 30 | 7 | 11 | 4 | 81.1 % (95 % CI: 65 %–92%) | 88.2 % (95 % CI: 73 %–97%) | 73.3 % (95 % CI: 45 %–92%) | 61.1 % (95 % CI: 36 %–83%) | 78.8 % (95 % CI: 65 %–89%) |
Endoscopists diminutive polyps ≤ 5 mm, n = 52 | 20 | 1 | 17 | 14 | 95.2 % (95 % CI: 76 %–100%) | 58.8 % (95 % CI: 41 %–75%) | 54.8 % (95 % CI: 36 %–73%) | 94.4 % (95 % CI: 73 %–100%) | 71.1 % (95 % CI: 57 %–83%) |
P value | 0.27 | 0.01 | 0.38 | 0.04 | 0.5 | ||||
ATENEA small polyps < 10 mm, n = 73 | 47 | 9 | 12 | 5 | 83.9 % (95 % CI: 72 %–92%) | 90.4 % (95 % CI: 79 %–97%) | 70.6 % (95 % CI: 44 %–90%) | 57.2 % (95 % CI: 34 %–78%) | 80.8 % (95 % CI: 70 %–89%) |
Endoscopists small polyps < 10 mm, n = 73 | 36 | 1 | 20 | 16 | 97.3 % (95 % CI: 86 %–100%) | 69.2 % (95 % CI: 55 %–81%) | 55.5 % (95 % CI: 38 %–72%) | 95.2 % (95 % CI: 76 %–100%) | 76.7 % (95 % CI: 65 %–86%) |
P value | 0.09 | 0.02 | 0.46 | 0.01 | 0.69 |
TP, true positive; FP, false positive; TN, true negative; FN, false negative; PPV, positive predictive value; SENS, sensitivity; NPV, negative predictive value; SPEC, specificity.