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Hirudin works out an inhibitory effect on both the overall phosphorylation of PDGFRβ and the downstream AKT pathway. (a) Western blot detection on the expressions of PDGFB, PDGFRβ, p-PDGFRβ, PI3K, p-PI3K, AKT, and p-AKT. (b) Semiquantitative analysis was performed based on the gray value. GAPDH was used for the endogenous protein. ##compared with the Model, P < 0.01.
