Table 3.

Results of pharmacokinetic parameters of labetalol

Pharmacokinetic parameter (unit)	Rogers et al. [48]	Saotome et al. [46]
N	8	7
Dosage	100 mg/8 h	150–450 mg/12 h
Elimination half-life (hours)	1.7 ± 0.27	5.8 ± 0.3 (4.3–6.9*)
Clearance (mL/kg/min)	21.8 ± 6.8	43.7 ± 5.2 (31.9–73.3*)
Time of maximum serum concentration (minutes)	20	NA
Tmax with food ingestion (minutes)	60	Approximately 60

Values are mean ± standard deviation

^*is a range