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. 2022 Jul 26;45(10):1643–1652. doi: 10.1038/s41440-022-00984-3

Table 3.

Results for age at baseline from 190 exercise studies

No. studies (participants) Fixed-effect meta-analysis Moderator analyses
Comparison Total Data available Mean difference (95% CI) Heterogeneity Sample size Allocation concealment Data from all participants
Endurance vs. control 131 (6754) 106 (5146) 0.0 (−0.3, 0.3) Q = 122.3, p = 0.12, I2 = 14.1% 0.00 (0.00, 0.00), p = 0.54 0.37 (−0.71, 1.44), p = 0.50 0.42 (−0.97, 0.14), p = 0.14
Resistance vs. control 45 (1481) 41 (1278) −0.3 (−0.6, −0.1) Q = 46.8, p = 0.21, I2 = 14.6% −0.04 (−0.08, −0.00), p = 0.06 1.05 (−1.92, 4.02), p = 0.49 −0.64 (−1.31, 0.04), p = 0.07
Isometric vs. control 12 (376) 10 (328) −0.4 (−1.5, 0.7) Q = 7.0, p = 0.64, I2 = 0.0% −0.04 (−0.15, −0.08), p = 0.55 NAa −0.59 (−4.33, 3.15), p = 0.76
Combined vs. control 25 (1254) 24 (1221) 0.0 (−0.6, 0.5) Q = 27.7, p = 0.23, I2 = 16.8% 0.00 (−0.01, 0.00), p = 0.64 −0.87 (−3.30, 1.56), p = 0.48 −1.20 (−2.28, −0.11), p = 0.03
Endurance vs. resistance 17 (533) 16 (496) 0.1 (−0.7, 0.8) Q = 17.3, p = 0.30, I2 = 13.4% −0.06 (−0.13, 0.01), p = 0.08 1.02 (−3.49, 5.53), p = 0.66 0.65 (−0.96, 2.26), p = 0.43
Endurance vs. combined 17 (536) 15 (447) 0.6 (−0.2, 1.3) Q = 10.6, p = 0.72, I2 = 0.0% 0.03 (−0.09, 0.16), p = 0.58 −0.15 (−1.50, 1.20), p = 0.83 0.76 (−0.86, 2.37), p = 0.36
Resistance vs. combined 9 (235) 9 (235) −0.4 (−1.6, 0.7) Q = 7.1, p = 0.53, I2 = 0.0% 0.08 (−0.15, 0.31), p = 0.50 1.59 (−6.36, 9.54), p = 0.69 −0.68 (−3.75, 2.39, p = 0.66
Endurance vs. isometric Not performed because only three studies were available for this analysis
Isometric vs. combined Not performed because only one study was available for this analysis

CI confidence interval, NA not available

aModerator analysis not performed because all studies were in the same subgroup