Table 1.
Differences between tumors of different sizes in adults
| Tumor < 1.5 cm | Tumor 1.5–3 cm | Tumor 3–5 cm | Tumor > 5 cm | P value* | |||||
|---|---|---|---|---|---|---|---|---|---|
| N | N | N | N | ||||||
| Age, years | 63 | 46.0 (21.0, 73.0) | 151 | 46.0 (18.0, 76.0 | 125 | 46.0 (19.0, 73.0) | 54 | 46.0 (18.0, 90.0) | 0.999 |
| Diagnostic delay, years | 53 | 3.0 (0.25, 19.0) | 128 | 3.0 (0.5, 20.0) | 109 | 3.0 (0.17, 27.0) | 48 | 5.5 (0.17, 21.0) | 0.032 |
| Phosphate, mmol/L | 63 | 0.48 (0.23, 0.87) | 151 | 0.48 (0.19, 0.90) | 125 | 0.45 (0.11, 1.03) | 54 | 0.42 (0.16, 0.90) | 0.320 |
| TmP/GFR, mmol/L | 31 | 0.36 (0.09, 1.30) | 72 | 0.39 (0.02, 1.25) | 52 | 0.36 (0.09, 1.50) | 17 | 0.31 (0.11, 0.74) | 0.768 |
| Calcium, mmol/L | 49 | 2.25 (1.10, 2.86) | 106 | 2.28 (2.00, 2.64)) | 88 | 2.26 (1.98, 10.50) | 37 | 2.30 (1.95, 2.70) | 0.146 |
| FGF23 xULN | 24 | 2.53 (0.56, 15.56) | 57 | 2.78 (0.13, 48.67) | 35 | 5.06 (0.28, 139.19) | 12 | 4.66 (1.03, 45.00) | 0.005 |
|
BMD T-score L1-L4 |
13 | − 2.7 (− 4.5, − 1.3) | 36 | − 3.1 (− 5.9, 0.1) | 12 | − 2.2 (− 4.8, − 1.1) | 10 | − 2.8 (− 6.9, − 1.2)) | 0.861 |
|
BMD T-score Total hip |
3 | − 2.6 (− 3.9, − 2.5) | 14 | − 2.5 (− 5.0, − 0.8) | 1 | − | 3 | − 2.9 (− 5.9, − 1.2) | 0.936 |
| BMD T-score femoral neck | 6 | − 3.4 (− 5.3, − 0.8) | 19 | − 2.8 (− 4.5, 0.4) | 6 | − 2.8 (− 4.6, − 2.2) | 5 | − 3.0 (− 3.6, − 1.5) | 0.749 |
| Tumor localization | 63 | 151 | 125 | 54 | 0.073 | ||||
| Lower limb | 41 (61.5%) | 78 (51.7%) | 55 (44.0%) | 25 (46.3%) | |||||
| Upper limb | 2 (3.2%) | 7 (4.6%) | 12 (9.6%) | 6 (11.1%) | |||||
| Head/neck | 10 (15.9%) | 39 (25.8%) | 30 (24.0%) | 9 (16.7%) | |||||
| Trunk | 6 (9.5%) | 10 (6.6%) | 12 (9.6%) | 10 (5.6%) | |||||
| Pelvis | 4 (6.3%) | 17 (11.3%) | 15 (12.0%) | 3 (5.6%) | |||||
| Multiple locations | 0 (0.0%) | 0 (0.0%) | 1 (0.8%) | 1 (1.9%) | |||||
*Differences between groups were tested using Mann Whitney-U test, Kruskal–Wallis test and chi-square test for homogeneity. Continous data are presented as median (range). Categorical data are presented as count (%)
BMD bone mineral density, FGF23 Fibroblast growth factor 23, TmP/GFR maximum tubular reabsorption rate of phosphate, xULN times the upper limit of normal