Table 2.
Geometric means of AUC and AUC fold change for each ELISA antigen.
| Geometric mean AUCs |
Geometric mean AUC fold change |
||||
|---|---|---|---|---|---|
| Timepoint/ vaccine | BNT162b2 G.M. AUC |
mRNA-1273 G.M. AUC |
BNT162b2 (G.M.F.I) |
mRNA-1273 (G.M.F.I) |
|
| Spike | Prime | 1569.32 | 2043.64 | 313.86 | 408.73 |
| Boost | 7405.92 | 7974.32 | 1481.18 | 1594.86 | |
| BNT162b2 LNP | Prime | 0.54 | 1.54 | 0.92 | 2.25 |
| Boost | 0.58 | 7.04 | 1.07 | 4.28 | |
| mRNA-1273 LNP | Prime | 0.55 | 1.84 | 1.1 | 2.6 |
| Boost | 0.66 | 8.62 | 1.32 | 12.2 | |
| Nonspecific LNP | Prime | 8.98 | 27.44 | 1.1 | 3.54 |
| Boost | 9.6 | 49.39 | 1.07 | 2.12 | |
| PEGylated BSA | Prime | 10.01 | 49.64 | 1.26 | 5.06 |
| Boost | 8.87 | 169.14 | 1.11 | 17.25 | |
| Low molecular weight PEG | Prime | 0.5 | 0.89 | 1 | 1.78 |
| Boost | 0.61 | 1.78 | 1.22 | 9.29 | |
| BSA | Prime | 5.43 | 5.38 | 0.92 | 0.96 |
| Boost | 5.78 | 8.06 | 0.98 | 1.44 | |
Geometric mean (G.M.) of all the area under the curve (AUC) values measured after the prime or the boost are shown in the left panels. Geometric mean of fold induction (G.M.F.I) values, expressed as the ratio between prime or boost AUCs and the baseline AUC for each of the participants is shown in the right panels. Prime: First SARS-CoV-2 vaccine dose; Boost: Second SARS-CoV-2 vaccine dose.