Table 1.
Characteristics | All n = 84 (%) |
Group A n = 42 (%) |
Group B n = 42 (%) |
p value |
---|---|---|---|---|
Sex | 0.693 | |||
Male | 77 (91.7) | 39 (92.9) | 38 (90.5) | |
Female | 7 (8.3) | 3 (7.1) | 4 (9.5) | |
Median age [range], years | 53.4 [30.0;75.0] | 52.7 [32.0;73.0] | 54.0 [30.0;75.0] | 0.578 |
BCLC stage | 0.693 | |||
C | 77 (91.7) | 38 (90.5) | 39 (92.9) | |
D | 7 (8.3) | 4 (9.5) | 3 (7.1) | |
Tumour number | 0.578 | |||
Single | 16 (19.0) | 9 (21.4) | 7 (16.7) | |
Multiple | 68 (81.0) | 33 (78.6) | 35 (83.3) | |
PVTT degree | 0.661 | |||
I+II | 16 + 30 (54.8) | 7 + 15 (52.4) | 9 + 15 (57.1) | |
III+IV | 29 + 9 (45.2) | 15 + 5 (47.6) | 14 + 4 (42.9) | |
Hepatitis B | 0.306 | |||
Yes | 80 (95.2) | 41 (97.6) | 39 (92.9) | |
No | 4 (4.8) | 1 (2.4) | 3 (7.1) | |
Child-Pugh class | 0.854 | |||
A | 26 (31.0) | 12 (28.6) | 14 (33.3) | |
B | 51 (60.7) | 26 (61.9) | 25 (59.5) | |
C | 7 (8.3) | 4 (9.5) | 3 (7.1) | |
Child-Pugh score, [range] | 7.4 [5;12] | 7.6 [5;12] | 7.2 [5;11] | 0.262 |
MELD score, [range] | 9.3 [4;15] | 9.5 [4;15] | 9.1 [6;14] | 0.427 |
MELD score | 0.212 | |||
≤ 11 | 72 (85.7) | 34 (81.0) | 38 (90.5) | |
> 11 | 12 (14.3) | 8 (19.0) | 4 (9.5) | |
Clinical symptom | 0.895 | |||
Variceal bleeding | 34 (40.5) | 17 (40.5) | 17 (40.5) | |
Refractory ascites/hydrothorax | 45 (53.6) | 22 (52.4) | 23 (54.8) | |
Variceal bleeding+refractory ascites | 5 (6.0) | 3 (7.1) | 2 (4.8) | |
AFP (ng/ml) | 0.821 | |||
≤ 400 | 31 (36.9) | 16 (38.1) | 15 (35.7) | |
> 400 | 53 (63.1) | 26 (61.9) | 27 (64.3) |
Notes: Unless otherwise indicated, data are the number of patients, with percentages in parentheses; Group A, transjugular intrahepatic portosystemic shunt (TIPS) plus sequential systemic therapy; Group B, only symptomatic and supportive treatment. p value ≤ 0.05 was considered to indicate statistical significance
Abbreviations: BCLC Barcelona Clinic Liver Cancer, PVTT, portal vein tumour thrombus, MELD Model for End-Stage Liver Disease, AFP alpha-fetoprotein